Endocrine Abstracts

Background: We assessed the effects of hydrochlorothiazide given alone and in combination with an ACEI on β-cell function in a negroid population to further explore possible ethnic differences in the effect of antihypertensive drugs on HOMA-IR.Materials and methods: Eighty newly diagnosed Nigerian essential hypertensive patients were assigned to receive either hydrochlorothiazide 25 mg daily or both hydrochlorothiazide and lisinopril (25/10 mg daily...

Background: Obesity contributes to the occurrence of many metabolic and cardiovascular complications including Type 2 diabetes, hypertension etc. Body adiposity is not just an energy store, but also an endocrine organ with elaboration of hormones and cytokines. Some of these cytokines have been implicated in the initiation and propagation of inflammation, and hence atherosclerosis.Aim: This study examined the relationship between high-sensitivity C-react...

Background: Gender specific differences appear particularly relevant in the overall management and outcome of type 2 diabetes mellitus (T2DM). We determined gender specific differences in cardio-metabolic risk, microvascular, and macrovascular complications in patients with T2DM.Method: Four hundred T2DM patients matched for age and disease duration were studied. Relevant clinical information, physical examination and laboratory data were analysed.<p...

A 56 year old female who was referred to the Endocrine clinic with a history of progressive anterior neck swelling, weight gain, memory impairment and sluggishness. On examination she was found to be pale, had an anterior neck mass which moved with swallowing but not with tongue protrusion, is diffuse, firm non tender, measuring 8 × 6 cm. There was associated submandibular lymph node enlargement.Her thyroid function test revealed primary hypothyroid...

Background: Type 2 diabetes mellitus (T2DM) is a potentially preventable disease that is presently increasing in epidemic proportion worldwide. Its onset can also be delayed with an appropriate and timely intervention if people at risk are identified early. This study determined risk levels of adults in Nigeria for type 2 DM by using Finnish Diabetes Risk Score (FINDRISC).Method: During our local activities for world diabetes day in 2011, adults who were...

Introduction: Diabetes mellitus is considered a cardiovascular risk equivalent. The presence of other cardiovascular risk factors in patients with diabetes may imply synergy for the occurrence and severity of cardiovascular morbidities and mortalities. Metabolic syndrome is the presence of these clusters of cardiovascular risks in an individual. Metabolic syndrome has been shown to be associated with some traditional risk factors and emerging risk factors.<p class="abstext...

Objective: The aim of this study was to compare psychological symptoms between diabetic patients, asthmatics and healthy individuals and also to determine the effect of these and other variables on quality of life among diabetes patients.Method: For each respondent the questionnaire on socio-demographic and clinical variables was completed. Each respondent also completed the General Health Questionnaire (GHQ 30), Zung’s Self Rating Depression Scale ...

Background: Diabetes Mellitus (DM) is increasing in prevalence worldwide. Sex differences in glycaemia attainment may be relevant in the management of type 2 DM.This study determined gender differences in glycaemic targets in patients with type 2 diabetes attending the Obafemi Awolowo University Teaching Hospital Complex (OAUTHC), Ile- Ife.Method: This cross-sectional descriptive study involved fou...

Background: A case report of Nigeria male who presented on account of bilateral gynaecomastia and was found to be azoospermic on investigation with a view to draw attention of clinicians to underling endocrine problems associated with gynaecomasia.Methodology: A case report of a 32 year old Nigeria man with progressive-bilateral breast enlargement was reviewed.Case report: A 32 year old Nigeri...

Background: Diabetes Mellitus (DM) is increasing in prevalence worldwide. Sex differences in glycaemia attainment may be relevant in the management of type 2 DM.This study determined gender differences in glycaemic targets in patients with type 2 diabetes attending the Obafemi Awolowo University Teaching Hospital Complex (OAUTHC), Ile- Ife.Method: This cross-sectional descriptive study involved fou...